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21216: API: Call blocked by Twilio


ERROR: 21216

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VOICE, TRUSTHUB
ERROR

Twilio blocked the outbound call before connecting it to the destination. This error can occur when the destination is classified as high risk for fraud, when the route cannot be used for regulatory reasons, or when you place a call to a +1 destination without a valid Primary Customer Profile on your account.

Possible causes

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  • The destination is in a high-risk fraud range that Twilio blocks to reduce exposure to toll fraud.
  • Regulatory restrictions prevent calls to the destination.
  • Your account is placing a call to a +1 destination and does not have a valid Primary Customer Profile. This can occur when:
    • Your account does not have a Primary Customer Profile.
    • Your account has an Individual Customer Profile that was approved after October 2025. Individual profiles approved after this date do not satisfy the Primary Customer Profile requirement for +1 calling.

Additional resources

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