In your response to Twilio's request, the response body is larger than 64 kB.
Possible Causes
The TwiML that you are serving is larger than 64 kB
You are serving non-TwiML content in your response; e.g. error message output
Possible Solutions
Verify that you are serving TwiML in your response to Twilio's request.
Verify that you are including this header in your TwiML response: <?xml version="1.0" encoding="UTF-8"?>
Limit your TwiML response to 64 kB or less.
Does your TwiML include the Play verb? Double-check the encoding and MIME type to ensure they are supported.
Check that your TwiML is formatted properly. To quickly verify your TwiML, you can copy and paste it into a new TwiML bin in the Twilio Console.
Check to see if your application is throwing errors. This may cause your application to send a large debug output back to Twilio instead of the expected TwiML.
If you are trying to send a 200 response in a status callback, use an empty TwiML response: <Response/>