---
page_type: error
code: 21408
message: >-
  21408: Message is blocked or permissions are disabled for the region indicated
  by the 'To' number
level: ERROR
product: Programmable Messaging
---

## Description

You have attempted to send an SMS or MMS to a region that has not been enabled in your account's [Messaging Geo-Permissions](https://console.twilio.com/us1/develop/sms/settings/geo-permissions) settings. These settings exist to help you ensure you only send SMS or MMS to the countries or regions you operate in, and avoid unexpected charges.

### Possible Causes

- You have attempted to send an SMS or MMS to a region that has not been enabled in your account's [Messaging Geo-Permissions](https://console.twilio.com/us1/develop/sms/settings/geo-permissions) settings. These settings exist to help you ensure you only send SMS or MMS to the countries or regions you operate in, and avoid unexpected charges.

- You have attempted to send a message to a region not supported by Twilio, such as traffic to recipients in Iran. For WhatsApp and RCS this includes all 'To' numbers that begin with the +98 prefix.

### Possible Solutions

If you wish to send messages to this region, please enable the relevant permissions on your account using the [Messaging Geographic Permissions](https://console.twilio.com/us1/develop/sms/settings/geo-permissions) page.

Note: To align with evolving regulatory requirements, Twilio has stopped delivering voice, messaging, and email traffic to recipients in Iran starting March 15, 2025 and Syria & Cuba starting September 15, 2025. Hence messages to Iran, Syria & Cuba can't be resumed using Geo Permissions.